03 — Omics

GoliathOmics

Genomics workflows on GoliathApp: sample alignment, QC, and process packs.

GoliathOmics inherits GoliathApp and uses the standalone utilitiesGoliathAlign andMethylExtractor, plus process packs. MethylExtractor is a performance-optimized fork of MethylDackel, focused on extraction. GoliathAlign and MethylExtractor do not require or know about GoliathApp or GoliathOmics, and GoliathApp does not reference GoliathOmics.

GoliathOmics specializes the GoliathApp platform for genomics. A SamplePrep instance aligns each sample, runs alignment QC and extraction QC against the baked configuration window plus any per-sample overlay, and leaves methylation matrices for later study steps. Process packs choose an analyte, a library technique, and a disease or trait cohort on the methylation, RNA-seq, or proteomics modality. Read alignment and methylation calling are the standalone utilities GoliathAlign and MethylExtractor.

Process packs

Analyte, assay-procedure, and application packs cover analytes, library techniques, and disease or trait studies for methylation, RNA-seq, and proteomics.

omics.goliathresearch.com will be the GoliathOmics site. In this repository that site is still a placeholder. It is not a running portal.